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Israeli Firm Galmed Reports Brain-Penetrating Drug Breakthrough

Galmed Pharmaceuticals has developed a brain-penetrating Aramchol formulation using nanotech, showing promise for Parkinson's and dementia treatments.

Science

Jerusalem, 10 April, 2026 (TPS-IL) — Israeli biopharmaceutical company Galmed Pharmaceuticals Ltd. announced a breakthrough development of a brain-penetrating formulation of its drug Aramchol, potentially advancing treatment for neurological diseases such as Parkinson’s and dementia.

Developed in collaboration with Nazareth-based Barcode Nanotech, the new formulation uses lipid nanoparticles to cross the blood-brain barrier, a major obstacle in treating central nervous system disorders. Early laboratory studies showed the drug reduced harmful protein aggregation linked to disease progression.

Galmed aims to begin early-stage clinical trials in Parkinson’s patients in the second half of 2026, pending regulatory guidance.

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